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CategoryGrowth Hormone Axis
Evidence gradeB Limited human data
Regulatory statusNot approved — research use only
Human amountsNone establishedDosing reference Study durations
FormatLyophilized vial
TypeSingle compound
Molecular formulaC38H49N9O5
Molecular weight711.9 g/mol
CAS number170851-70-4
SequenceAib-His-D-2-Nal-D-Phe-Lys-NH2
References11
SummaryIpamorelin is a synthetic pentapeptide that activates the ghrelin receptor and stimulates growth hormone release, studied in laboratory models and in a small number of human pharmacology and phase 2 studies. It has no approved use, and its one controlled efficacy trial, in postoperative ileus, did not show a significant difference from placebo. Evidence in humans for any other use has not been published in the sources reviewed.
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