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For research use only. Not for human or veterinary use. Not a drug, food, or dietary supplement.
Cycle-length evidence

Cortagen cycle length: what human studies ran

Not approved — research use onlyCPreclinical research
Short answer: there is no established Cortagen cycle length, and we found no human studies that report one.

Treatment and follow-up in human studies

No human study durations are recorded.

What has not been tested

  • On-and-off schedules or breaks between courses.
  • Repeated courses and long-term exposure beyond the periods listed.
  • Cortagen combined with other compounds, unless a study above says so.

Frequently asked questions

Is there an established Cortagen cycle length?
No. We found no human studies that report a treatment duration for Cortagen.
What is the longest human study of Cortagen?
None is recorded.
Do study durations tell me how long to use something?
No. A study duration is how long investigators administered a compound to selected participants under monitoring. It is not a recommended course, and a break between courses has not been tested for any compound on this site that is not approved.

References

  1. Effect of tetrapeptide cortagen on regeneration of sciatic nerve Bulletin of Experimental Biology and Medicine. 2000
  2. The delayed effect of cortagen on the restoration of injured nerve function Doklady Biological Sciences. 2002
  3. Tissue-specific effects of peptides Bulletin of Experimental Biology and Medicine. 2001
  4. Elucidation of the effect of brain cortex tetrapeptide Cortagen on gene expression in mouse heart by microarray Neuroendocrinology Letters. 2004
  5. Effects of short peptides on thymocyte blast transformation and signal transduction along the sphingomyelin pathway Bulletin of Experimental Biology and Medicine. 2002
  6. In vitro effect of short peptides on expression of interleukin-2 gene in splenocytes Bulletin of Experimental Biology and Medicine. 2002
  7. Effects of short peptides on lymphocyte chromatin in senile subjects Bulletin of Experimental Biology and Medicine. 2004
  8. Effects of epithalon and cortagene on immunity and hemostasis in neonatally hypophysectomized chicken and old birds (Russian) Advances in Gerontology. 2008
  9. Effects of bioactive tetrapeptides on free-radical processes Bulletin of Experimental Biology and Medicine. 2007
  10. Tissue-specific action of peptides in tissue culture of rats of various ages (Russian) Advances in Gerontology. 2002
  11. Epigenetic modification under the influence of peptide bioregulators on the "old" chromatin Georgian Medical News. 2023
  12. Cortexin and cortagen as correcting agents in functional and metabolic disorders in the brain in chronic ischemia (Russian) Eksperimentalnaia i Klinicheskaia Farmakologiia. 2011
  13. Bulk Drug Substances Nominated for Use in Compounding Under Section 503A of the Federal Food, Drug, and Cosmetic Act (updated May 14, 2026) FDA. 2026
  14. Cortagen (CID 18439621): compound summary and computed properties PubChem. 2026
  15. PubMed search for Cortagen (approximately 15 records) and ClinicalTrials.gov search (no registered studies) PubMed / ClinicalTrials.gov. 2026
  16. Production of lymphocyte-activating factors by mouse macrophages during aging and under the effect of short peptides Bulletin of Experimental Biology and Medicine. 2006
  17. World Anti-Doping Code International Standard Prohibited List 2026 WADA. 2026
  18. [Neuroprotective effects of peptides bioregulators in people of various age] Adv Gerontol. 2013