Cycle-length evidence
Cortagen cycle length: what human studies ran
Not approved — research use onlyCPreclinical research
Short answer: there is no established Cortagen cycle length, and we found no human studies that report one.
Treatment and follow-up in human studies
No human study durations are recorded.
What has not been tested
- On-and-off schedules or breaks between courses.
- Repeated courses and long-term exposure beyond the periods listed.
- Cortagen combined with other compounds, unless a study above says so.
Frequently asked questions
Is there an established Cortagen cycle length?
No. We found no human studies that report a treatment duration for Cortagen.
What is the longest human study of Cortagen?
None is recorded.
Do study durations tell me how long to use something?
No. A study duration is how long investigators administered a compound to selected participants under monitoring. It is not a recommended course, and a break between courses has not been tested for any compound on this site that is not approved.
References
- Effect of tetrapeptide cortagen on regeneration of sciatic nerve Bulletin of Experimental Biology and Medicine. 2000
- The delayed effect of cortagen on the restoration of injured nerve function Doklady Biological Sciences. 2002
- Tissue-specific effects of peptides Bulletin of Experimental Biology and Medicine. 2001
- Elucidation of the effect of brain cortex tetrapeptide Cortagen on gene expression in mouse heart by microarray Neuroendocrinology Letters. 2004
- Effects of short peptides on thymocyte blast transformation and signal transduction along the sphingomyelin pathway Bulletin of Experimental Biology and Medicine. 2002
- In vitro effect of short peptides on expression of interleukin-2 gene in splenocytes Bulletin of Experimental Biology and Medicine. 2002
- Effects of short peptides on lymphocyte chromatin in senile subjects Bulletin of Experimental Biology and Medicine. 2004
- Effects of epithalon and cortagene on immunity and hemostasis in neonatally hypophysectomized chicken and old birds (Russian) Advances in Gerontology. 2008
- Effects of bioactive tetrapeptides on free-radical processes Bulletin of Experimental Biology and Medicine. 2007
- Tissue-specific action of peptides in tissue culture of rats of various ages (Russian) Advances in Gerontology. 2002
- Epigenetic modification under the influence of peptide bioregulators on the "old" chromatin Georgian Medical News. 2023
- Cortexin and cortagen as correcting agents in functional and metabolic disorders in the brain in chronic ischemia (Russian) Eksperimentalnaia i Klinicheskaia Farmakologiia. 2011
- Bulk Drug Substances Nominated for Use in Compounding Under Section 503A of the Federal Food, Drug, and Cosmetic Act (updated May 14, 2026) FDA. 2026
- Cortagen (CID 18439621): compound summary and computed properties PubChem. 2026
- PubMed search for Cortagen (approximately 15 records) and ClinicalTrials.gov search (no registered studies) PubMed / ClinicalTrials.gov. 2026
- Production of lymphocyte-activating factors by mouse macrophages during aging and under the effect of short peptides Bulletin of Experimental Biology and Medicine. 2006
- World Anti-Doping Code International Standard Prohibited List 2026 WADA. 2026
- [Neuroprotective effects of peptides bioregulators in people of various age] Adv Gerontol. 2013