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For research use only. Not for human or veterinary use. Not a drug, food, or dietary supplement.
AMIRAVOResearch Library
Cycle-length evidence

Humanin cycle length: what human studies ran

Not approved — research use onlyCPreclinical research
Short answer: there is no established Humanin cycle length, and we found no human studies that report one.

Treatment and follow-up in human studies

No human study durations are recorded.

What has not been tested

  • On-and-off schedules or breaks between courses.
  • Repeated courses and long-term exposure beyond the periods listed.
  • Humanin combined with other compounds, unless a study above says so.

Frequently asked questions

Is there an established Humanin cycle length?
No. We found no human studies that report a treatment duration for Humanin.
What is the longest human study of Humanin?
None is recorded.
Do study durations tell me how long to use something?
No. A study duration is how long investigators administered a compound to selected participants under monitoring. It is not a recommended course, and a break between courses has not been tested for any compound on this site that is not approved.
Humanin dosing reference Full research page

References

  1. Detailed characterization of neuroprotection by a rescue factor humanin against various Alzheimer's disease-relevant insults Journal of Neuroscience. 2001
  2. Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis Proceedings of the National Academy of Sciences. 2003
  3. Humanin binds and nullifies Bid activity by blocking its activation of Bax and Bak Journal of Biological Chemistry. 2005
  4. Humanin and the receptors for humanin Molecular Neurobiology. 2010
  5. Identification of soluble WSX-1 not as a dominant-negative but as an alternative functional subunit of a receptor for an anti-Alzheimer's disease rescue factor Humanin Biochemical and Biophysical Research Communications. 2009
  6. Humanin: a novel central regulator of peripheral insulin action PLoS ONE. 2009
  7. Circulating humanin levels are associated with preserved coronary endothelial function American Journal of Physiology - Heart and Circulatory Physiology. 2013
  8. Acute endurance exercise stimulates circulating levels of mitochondrial-derived peptides in humans Journal of Applied Physiology. 2021
  9. Disease-specific plasma levels of mitokines FGF21, GDF15, and Humanin in type II diabetes and Alzheimer's disease in comparison with healthy aging GeroScience. 2021
  10. Evaluation of Serum Humanin and MOTS-c Peptide Levels in Patients with COVID-19 and Healthy Subjects Current Protein and Peptide Science. 2023
  11. The mitochondrial-derived peptide MOTS-c promotes metabolic homeostasis and reduces obesity and insulin resistance Cell Metabolism. 2015
  12. Humanin: Functional Interfaces with IGF-I Growth Hormone & IGF Research. 2016
  13. World Anti-Doping Code International Standard Prohibited List 2026 WADA. 2026
  14. openFDA drug label search for humanin as substance name (no matches) FDA openFDA API. 2026
  15. ClinicalTrials.gov search for studies naming humanin (biomarker studies only; e.g. NCT03431844, Humanin Isoforms in Cardiac Muscle and Blood Plasma) ClinicalTrials.gov. 2026
  16. Role of humanin, a mitochondrial-derived peptide, in cardiovascular disorders Archives of Cardiovascular Diseases. 2020
  17. Bulk Drug Substances Nominated for Use in Compounding Under Section 503A of the Federal Food, Drug, and Cosmetic Act (updated May 14, 2026) FDA. 2026