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For research use only. Not for human or veterinary use. Not a drug, food, or dietary supplement.
Cycle-length evidence

Melanotan II cycle length: what human studies ran

Not approved — research use onlyBLimited human data
Short answer: there is no established Melanotan II cycle length, and we found no human studies that report one.

Treatment and follow-up in human studies

No human study durations are recorded.

What has not been tested

  • On-and-off schedules or breaks between courses.
  • Repeated courses and long-term exposure beyond the periods listed.
  • Melanotan II combined with other compounds, unless a study above says so.

Frequently asked questions

Is there an established Melanotan II cycle length?
No. We found no human studies that report a treatment duration for Melanotan II.
What is the longest human study of Melanotan II?
None is recorded.
Do study durations tell me how long to use something?
No. A study duration is how long investigators administered a compound to selected participants under monitoring. It is not a recommended course, and a break between courses has not been tested for any compound on this site that is not approved.

References

  1. Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study Life Sci. 1996
  2. Synthetic melanotropic peptide initiates erections in men with psychogenic erectile dysfunction: double-blind, placebo controlled crossover study J Urol. 1998
  3. Effect of an alpha-melanocyte stimulating hormone analog on penile erection and sexual desire in men with organic erectile dysfunction Urology. 2000
  4. Melanocortin peptide therapeutics: historical milestones, clinical studies and commercialization Peptides. 2006
  5. Role of melanocortinergic neurons in feeding and the agouti obesity syndrome Nature. 1997
  6. Cyclic lactam alpha-melanotropin analogues of Ac-Nle4-cyclo[Asp5, D-Phe7,Lys10] alpha-melanocyte-stimulating hormone-(4-10)-NH2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin receptors J Med Chem. 1995
  7. Risks of unregulated use of alpha-melanocyte-stimulating hormone analogues: a review Int J Dermatol. 2017
  8. Melanoma associated with the use of melanotan-II Dermatology. 2014
  9. Atypical melanocytic naevi following melanotan injection Ir Med J. 2013
  10. Melanotan-induced priapism: a hard-earned tan BMJ Case Rep. 2019
  11. [The risks of tanning with the Barbie drug] Ned Tijdschr Geneeskd. 2022
  12. Identification and characterization by LC-UV-MS/MS of melanotan II skin-tanning products sold illegally on the Internet Drug Test Anal. 2015
  13. Melanotan II nasal spray: a possible risk factor for oral mucosal malignant melanoma? Int J Oral Maxillofac Surg. 2025
  14. Changes in Oral Mucosa Associated with Melanotan II Injections: A Case Report Life (Basel). 2026
  15. Import Alert 66-41: Detention Without Physical Examination of Unapproved New Drugs Promoted in the U.S. FDA. 2026
  16. WADA Prohibited List US Food and Drug Administration. 2026
  17. Melanotan II (CID 92432) PubChem. 2026
  18. DailyMed drug label search for melanotan II (zero labels returned on 22 Oct 2026) DailyMed (NLM). 2026