Cycle-length evidence
Melanotan II cycle length: what human studies ran
Not approved — research use onlyBLimited human data
Short answer: there is no established Melanotan II cycle length, and we found no human studies that report one.
Treatment and follow-up in human studies
No human study durations are recorded.
What has not been tested
- On-and-off schedules or breaks between courses.
- Repeated courses and long-term exposure beyond the periods listed.
- Melanotan II combined with other compounds, unless a study above says so.
Frequently asked questions
Is there an established Melanotan II cycle length?
No. We found no human studies that report a treatment duration for Melanotan II.
What is the longest human study of Melanotan II?
None is recorded.
Do study durations tell me how long to use something?
No. A study duration is how long investigators administered a compound to selected participants under monitoring. It is not a recommended course, and a break between courses has not been tested for any compound on this site that is not approved.
References
- Evaluation of melanotan-II, a superpotent cyclic melanotropic peptide in a pilot phase-I clinical study Life Sci. 1996
- Synthetic melanotropic peptide initiates erections in men with psychogenic erectile dysfunction: double-blind, placebo controlled crossover study J Urol. 1998
- Effect of an alpha-melanocyte stimulating hormone analog on penile erection and sexual desire in men with organic erectile dysfunction Urology. 2000
- Melanocortin peptide therapeutics: historical milestones, clinical studies and commercialization Peptides. 2006
- Role of melanocortinergic neurons in feeding and the agouti obesity syndrome Nature. 1997
- Cyclic lactam alpha-melanotropin analogues of Ac-Nle4-cyclo[Asp5, D-Phe7,Lys10] alpha-melanocyte-stimulating hormone-(4-10)-NH2 with bulky aromatic amino acids at position 7 show high antagonist potency and selectivity at specific melanocortin receptors J Med Chem. 1995
- Risks of unregulated use of alpha-melanocyte-stimulating hormone analogues: a review Int J Dermatol. 2017
- Melanoma associated with the use of melanotan-II Dermatology. 2014
- Atypical melanocytic naevi following melanotan injection Ir Med J. 2013
- Melanotan-induced priapism: a hard-earned tan BMJ Case Rep. 2019
- [The risks of tanning with the Barbie drug] Ned Tijdschr Geneeskd. 2022
- Identification and characterization by LC-UV-MS/MS of melanotan II skin-tanning products sold illegally on the Internet Drug Test Anal. 2015
- Melanotan II nasal spray: a possible risk factor for oral mucosal malignant melanoma? Int J Oral Maxillofac Surg. 2025
- Changes in Oral Mucosa Associated with Melanotan II Injections: A Case Report Life (Basel). 2026
- Import Alert 66-41: Detention Without Physical Examination of Unapproved New Drugs Promoted in the U.S. FDA. 2026
- WADA Prohibited List US Food and Drug Administration. 2026
- Melanotan II (CID 92432) PubChem. 2026
- DailyMed drug label search for melanotan II (zero labels returned on 22 Oct 2026) DailyMed (NLM). 2026