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| Attribute |  |
|---|---|
| Category | Skin |
| Evidence grade | B Limited human data |
| Regulatory status | Not approved — research use only |
| Human amounts | None establishedDosing reference Study durations |
| Format | |
| Type | Single compound |
| Molecular formula | Not listed |
| Molecular weight | 889 g/mol |
| CAS number | 616204-22-9 |
| Sequence | Ac- |
| References | 12 |
| Summary | Argireline is the trade name of acetyl hexapeptide-8, a cosmetic ingredient modelled on part of the SNAP-25 protein and marketed as a topical alternative to botulinum toxin; the small human studies located are mixed, including a double-blind split-face study that found no significant difference from the vehicle, and the proposed neuromuscular mechanism has not been demonstrated for it. |