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| Attribute |  |
|---|---|
| Category | Skin |
| Evidence grade | B Limited human data |
| Regulatory status | Not approved — research use only |
| Human amounts | None establishedDosing reference Study durations |
| Format | |
| Type | Single compound |
| Molecular formula | C39H75N7O10 |
| Molecular weight | 802.1 g/mol |
| CAS number | 214047-00-4 |
| Sequence | Palmitoyl- |
| References | 11 |
| Summary | Matrixyl is the trade name of palmitoyl pentapeptide-4 (pal-KTTKS), a cosmetic ingredient based on a fragment of type I procollagen with a palmitic acid tail; the main human study is a 12-week industry split-face trial in 93 women reporting reduced fine lines versus the same moisturizer without it, with cell work suggesting collagen stimulation and skin studies showing poor permeation. |