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CategoryLongevity
Evidence gradeA Human trial evidence
Regulatory statusFDA-approved
Human amountsFDA labelDosing reference Study durations
FormatBottle
TypeSingle compound
Molecular formulaC16H18ClN3S
Molecular weight319.9 g/mol
CAS number61-73-4
SequenceNot listed
References7
SummaryMethylene blue is a thiazine dye and oxidation-reduction agent, not a peptide. It is FDA-approved as PROVAYBLUE injection for treating acquired methemoglobinemia in children and adults, with a boxed warning for serotonin syndrome when combined with serotonergic drugs or opioids, and it is contraindicated in G6PD deficiency. It has also been studied in small human trials, for example in septic shock and brain imaging; this entry summarizes the label and selected studies for research reference only.
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