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Attribute
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CategoryMetabolic
Evidence gradeA Human trial evidence
Regulatory statusApproved, no longer marketed
Human amountsFDA labelDosing reference Study durations
Format
TypeSingle compound
Molecular formulaC171H267N51O53S2
Molecular weight3,949.4 g/mol
CAS number151126-32-8
SequenceLys-Cys-Asn-Thr-Ala-Thr-Cys-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Pro-Ile-Leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn-Thr-Tyr-NH2
References6
SummaryPramlintide is a synthetic 37-amino-acid analog of human amylin, FDA-approved in 2005 as Symlin for adjunctive use with mealtime insulin in type 1 and type 2 diabetes; Drugs@FDA now lists all Symlin products as discontinued.
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