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| Attribute |  |
|---|---|
| Category | Metabolic |
| Evidence grade | A Human trial evidence |
| Regulatory status | FDA-approved |
| Human amounts | FDA labelDosing reference Study durations |
| Format | Lyophilized vial |
| Type | Single compound |
| Molecular formula | C187H291N45O59 |
| Molecular weight | 4,114 g/mol |
| CAS number | Not listed |
| Sequence | Not listed |
| References | 10 |
| Summary | Semaglutide is a modified version of the gut hormone GLP-1 that is approved by the FDA, in injectable and oral forms, for type 2 diabetes, chronic weight management, cardiovascular risk reduction and related indications. Large randomized trials have studied its effects on body weight, cardiovascular events and kidney outcomes, and the most frequently reported adverse events are gastrointestinal. This entry summarizes the FDA labels and published trials for research reference only. |