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- PubMedPotassium-Competitive Acid Blocker Increases Ileal Permeability and Exacerbates Ileal Inflammation under Stress Conditions in a Mouse Model of Eosinophilic Enteritis.Digestion · 2026 Apr 20
- PubMedReviewCoeliac disease and the intestinal barrier: mechanisms of disruption and strategies for restoration.Gut · 2026 Mar 6
- PubMedReviewIntegrated Role of Microbial, Fungal, and Plant-Derived Interventions in the Management of Celiac Disease: A Narrative Review.Cureus · 2026 Jan
- PubMedPreventive effects of Larazotide acetate (AT-1001) on non-alcoholic fatty liver diseases (NAFLD) in a mouse model.Pediatrics and neonatology · 2026 Jan
- PubMedResearch Support, Non-U.S. Gov'tAntibacterial hyaluronic acid hydrogel with sustained release of larazotide as effective colitis treatment.Journal of controlled release : official journal of the Controlled Release Society · 2025 Nov 10
- PubMedLarazotide Acetate Protects the Intestinal Mucosal Barrier from Anoxia/Reoxygenation Injury via Various Cellular Mechanisms.Biomedicines · 2025 Oct 12
- PubMedReviewIs There a Future Without Gluten Restrictions for Celiac Patients? Update on Current Treatments.Nutrients · 2025 Sep 15
- PubMedRandomized Controlled TrialClinical Trial, Phase IIResearch Support, Non-U.S. Gov'tViral spike antigen clearance and augmented recovery in children with post-COVID multisystem inflammatory syndrome treated with larazotide.Science translational medicine · 2025 Jul 30
- PubMedThe PAR2 Antagonist Larazotide Can Mitigate Acute Histamine-Stimulated Epithelial Barrier Disruption in Keratinocytes: A Potential Adjunct Treatment for Atopic Dermatitis.JID innovations : skin science from molecules to population health · 2025 Jul
- PubMedReviewNew Therapeutic Challenges in Pediatric Gastroenterology: A Narrative Review.Healthcare (Basel, Switzerland) · 2025 Apr 17
- PubMedReviewElucidating the Significance of Zonulin in the Pathogenesis of Chronic Inflammatory Disorders: Emphasis on Intestinal Barrier Function and Tight Junction Regulation.Current medicinal chemistry · 2025
- PubMedSystematic ReviewCeliac disease: Hope for new treatments beyond a gluten-free diet.Clinical nutrition (Edinburgh, Scotland) · 2024 Jun
- PubMedAmeliorative Effects of Larazotide Acetate on Intestinal Permeability and Bacterial Translocation in Acute Pancreatitis Model in Rats.Digestive diseases and sciences · 2024 Apr
- PubMedBromelain and ficin proteolytic effects on gliadin cytotoxicity and expression of genes involved in cell-tight junctions in Caco-2 cells.Amino acids · 2023 Nov
- PubMedReviewZonulin as a Potential Therapeutic Target in Microbiota-Gut-Brain Axis Disorders: Encouraging Results and Emerging Questions.International journal of molecular sciences · 2023 Apr 19
- PubMedResearch Support, Non-U.S. Gov'tTargeting endothelial tight junctions to predict and protect thoracic aortic aneurysm and dissection.European heart journal · 2023 Apr 7
- PubMedSex-dependent Lupus Blautia (Ruminococcus) gnavus strain induction of zonulin-mediated intestinal permeability and autoimmunity.Frontiers in immunology · 2022
- PubMedReviewCeliac Disease and Targeting the Molecular Mechanisms of Autoimmunity in COVID Pandemic.International journal of molecular sciences · 2022 Jul 13
- PubMedTight junction regulation in celiac disease: role of larazotide acetate.Minerva gastroenterology · 2022 Mar
- PubMedZonulin Antagonist, Larazotide (AT1001), As an Adjuvant Treatment for Multisystem Inflammatory Syndrome in Children: A Case Series.Critical care explorations · 2022 Feb
- PubMedMeta-AnalysisSystematic ReviewLarazotide acetate for treatment of celiac disease: A systematic review and meta-analysis of randomized controlled trials.Clinics and research in hepatology and gastroenterology · 2022 Jan
- PubMedEffects of larazotide acetate, a tight junction regulator, on the liver and intestinal damage in acute liver failure in rats.Human & experimental toxicology · 2021 Dec
- PubMedReviewCurrent pharmacological approaches and potential future therapies for Celiac disease.European journal of pharmacology · 2021 Oct 15
- PubMedPeptide Derivatives of the Zonulin Inhibitor Larazotide (AT1001) as Potential Anti SARS-CoV-2: Molecular Modelling, Synthesis and Bioactivity Evaluation.International journal of molecular sciences · 2021 Aug 30
- PubMedResearch Support, N.I.H., ExtramuralResearch Support, Non-U.S. Gov'tMultisystem inflammatory syndrome in children is driven by zonulin-dependent loss of gut mucosal barrier.The Journal of clinical investigation · 2021 Jul 15
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