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Attribute
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CategoryMetabolic
Evidence gradeC Preclinical research
Regulatory statusNot approved — research use only
Human amountsNone establishedDosing reference Study durations
Format
TypeSingle compound
Molecular formulaC111H206N36O28S2
Molecular weight2,557.2 g/mol
CAS number859216-15-2
SequenceCKGGRAKDC-GG-D(KLAKLAK)2 (cyclic Cys-Lys-Gly-Gly-Arg-Ala-Lys-Asp-Cys homing motif, Gly-Gly linker, D-enantiomer Lys-Leu-Ala-Lys-Leu-Ala-Lys repeat)
References8
SummaryAdipotide is a synthetic peptidomimetic designed to deliver a pro-apoptotic sequence to blood vessels of white fat; the primate study that defined it reported reversible renal proximal tubule changes at the doses judged optimal, and its single registered human trial was terminated after 4 participants with no results posted.
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