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| Attribute |  |
|---|---|
| Category | Metabolic |
| Evidence grade | A Human trial evidence |
| Regulatory status | Investigational |
| Human amounts | Trial dosesDosing reference Study durations |
| Format | |
| Type | Single compound |
| Molecular formula | Not listed |
| Molecular weight | Not listed |
| CAS number | Not listed |
| Sequence | Not listed |
| References | 13 |
| Summary | MariTide (maridebart cafraglutide, AMG 133) is not a peptide but an antibody-peptide conjugate: synthetic GLP-1 receptor agonist peptides chemically attached to an anti-GIP-receptor monoclonal antibody, investigational for obesity, with a 592-participant phase 2 trial reporting body-weight change of -12.3% to -16.2% at 52 weeks and phase 3 trials under way. |