Blends · Dosing reference

Selank + Semax Blend dosage

What the human evidence does and does not show, how long studies ran, and the arithmetic for working with vials.

Not approved — research use onlyNone established

Full research page Cycle-length evidence Compare Prefer Amiravo on Google

Regulatory status: Not approved — research use only
Human amounts: None established in humans
Route studied: —
Frequency: Not established
Half-life: Not established
Evidence grade: Not yet assessed
Vial sizes on the market: 10 mg
Other forms seen: Liquid spray 10 mL (10 mg combined) · Dissolving strips (20 per pack)

What Selank + Semax Blend is

This blend pairs Selank and Semax, two synthetic neuropeptides originally developed in Russia, studied in research on stress response and neuronal function.

No mechanistic study of Selank and Semax administered together was identified, so no combined mechanism is described ^8. The components are summarised separately below and each has its own page. Components Selank ( /library/selank ): radioligand binding experiments on brain cell membranes reported that Selank acted as a positive allosteric modulator of tritiated GABA binding, and the authors proposed allosteric… How it works →

Key evidence

Vanhee et al., Drug Test Anal · 2020 · Seized pharmaceutical preparations
Identified Selank and Semax in two seized preparations, reported that neither compound had completed clinical trials to the authors' knowledge, and documented wide online availability as powders and nasal sprays. ⁴
Kolomin et al., Front Pharmacol · 2016 · Rats (frontal cortex gene expression)
Selank administration alone was associated with changed expression of 45 neurotransmission-related genes at one hour and 22 at three hours, correlating with changes caused by GABA. ²
Dolotov et al., J Neurochem · 2006 · Rats (basal forebrain)
Semax alone showed specific, reversible, calcium-dependent membrane binding, and intranasal administration was associated with a rapid rise in basal forebrain BDNF protein but not in cerebellum. ³

All studies on the research page

What the human evidence shows

No approved or established human dose

We searched PubMed and ClinicalTrials.gov and found no human studies that administered Selank + Semax Blend. The research described on its page is from cells or animals, and animal amounts do not translate to people.

How long did human studies run?

No human study durations are recorded for Selank + Semax Blend.

Cycle-length evidence for Selank + Semax Blend

Selank + Semax Blend draw calculator

Pick the vial strength and the water added, enter an amount, and see the concentration, the units to draw and how many draws the vial holds. Arithmetic only.

1 · Vial strength

sizes on the market

2 · Water added

3 · Amount per draw

4 · Syringe

Your mix

10 mg + 2 mL water = 5 mg/mL

10 units holds 0.5 mg (500 mcg)

Draw toEnter an amount in step 3

U-100 syringe · 100 units = 1 mL

Computed from your inputs. Not a dose or a recommendation.

Compare water volumes for this vialShow

More water = lower concentration = a larger, easier-to-measure draw. Tap a row to use it.

Water	mg/mL	Draw
0.5 mL	20	—
1 mL	10	—
1.5 mL	6.667	—
2 mL	5	—
2.5 mL	4	—
3 mL	3.333	—
5 mL	2	—

Supplies and handling

Lyophilized vial
Sealed vial with the freeze-dried cake. Check the label, lot and the certificate of analysis before opening.
Sterile diluent
The diluent named on the product documentation. Bacteriostatic water contains benzyl alcohol; sterile water does not.
Graduated syringes
Sized to the volume being measured. U-100 insulin syringes are graduated in units where 100 units = 1 mL.
Alcohol prep pads
For wiping vial stoppers before each puncture.
Nitrile gloves
Clean gloves for aseptic handling.
Sharps container
Puncture-resistant container for used needles.

Step-by-step reconstitution guide Storage and transport accessories

Storage

General research-context handling only, and there is an added consideration for a multi-component vial: the two components are separate molecules with separate stability and solubility behaviour, and no published stability data for them combined in one container were identified. Defer to the supplier's own stability and handling documentation for the specific lot. No preparation or administration instructions are given on this page.

Lyophilized (unmixed) vials: typically stored cold and dry, away from light, as the documentation directs. Many are stable longer frozen.
Reconstituted vials: typically refrigerated (about 2–8 °C), protected from light and not frozen.
Bacteriostatic water contains benzyl alcohol, which inhibits bacterial growth in multi-use vials; sterile water has no preservative.

Handling mistakes and troubleshooting

Added the wrong volume of diluent: The concentration changes, not the amount of compound in the vial. Recalculate with the volume actually added and relabel the vial.
Shook the vial and it foamed: Let it settle in the refrigerator. Foam is a sign of agitation; some peptides aggregate when shaken. Note it on the label.
The solution is cloudy or has particles: Do not use it. Cloudiness can indicate incomplete dissolution, contamination or degradation. Record the lot and contact the supplier with the certificate of analysis.
The powder cake looks melted or shrunken before reconstitution: This can indicate the vial was exposed to heat or moisture. Record the lot and condition on arrival.
Liquid sprayed back when the needle was removed: Pressure built up in the vial. Withdraw a small volume of air while adding diluent to keep pressure neutral.

Regulatory status

Status: Neither peptide is approved by the FDA for any indication, and no DailyMed drug label for either was found ^4,6. A 2020 analysis of seized pharmaceutical preparations containing Selank and Semax stated that, to its authors' knowledge, neither compound had completed any clinical trials ^4. Neither substance appears on FDA's May 14, 2026 503A bulk drug substances list in any category ^7.
United States (FDA): Neither Selank nor Semax has an approved FDA application, and DailyMed name searches for both returned no drug labels ^4,6. Neither appears in category 1, 2 or 3 of FDA's May 14, 2026 503A bulk drug substances list ^7. Both have been reported in seized unlicensed preparations in Europe ^4.
Sport (WADA): Neither Selank nor Semax is named in the WADA 2026 Prohibited List ^9. That absence is not permission: section S0, Non-Approved Substances, prohibits at all times any pharmacological substance not addressed by a later section and with no current approval by any governmental regulatory health authority for human therapeutic use, and introduces its examples with "including but not limited to" ^9. An athlete would need to resolve the status of an unapproved peptide with the relevant anti-doping organisation rather than infer it from the absence of a name ^9.

Status varies by country and changes over time. How we describe regulatory status.

Selank + Semax Blend compared with related compounds

Compound	Status	Evidence	Human amounts	Half-life
Selank + Semax Blend	Not approved — research use only	—	None established	—
Cerebrolysin	Approved outside the US	A	Ex-US label	Not directly measurable (peptide mixture
Selank	Approved outside the US	B	None established	—
Semax	Approved outside the US	B	None established	—
BPC-157 + TB-500 Blend	Not approved — research use only	C	None established	—
CJC-1295 (no DAC) + Ipamorelin Blend	Not approved — research use only	—	None established	—

Frequently asked questions

What doses of Selank + Semax Blend have been studied in humans?

None that establish an amount. Selank + Semax Blend is not approved anywhere and we found no human studies that administered it. Amiravo does not publish community or vendor figures.

Is there an established Selank + Semax Blend cycle length?

No. We found no human studies that report treatment duration for Selank + Semax Blend.

How much bacteriostatic water should be added to a Selank + Semax Blend vial?

There is no compound-specific volume. The diluent volume only sets the concentration: concentration = mass in the vial ÷ volume added (for example, 10 mg in 2 mL gives 5 mg/mL). The calculator on this page shows the arithmetic for any combination.

How many units is a given amount on an insulin syringe?

On a U-100 syringe, 100 units = 1 mL. Units for an amount = amount ÷ (concentration per unit). The calculator converts any amount you enter at the concentration you choose; a unit is a volume mark, not an amount of compound.

Is Selank + Semax Blend FDA-approved?

Not approved — research use only. Neither peptide is approved by the FDA for any indication, and no DailyMed drug label for either was found ^4,6. A 2020 analysis of seized pharmaceutical preparations containing Selank and Semax stated that, to its authors' knowledge, neither compound had completed any clinical trials ^4. Neither substance appears on FDA's May 14, 2026 503A bulk drug substances list in any category ^7.

References

Peptide-based Anxiolytics: The Molecular Aspects of Heptapeptide Selank Biological Activity Protein Pept Lett. 2018
Selank Administration Affects the Expression of Some Genes Involved in GABAergic Neurotransmission Front Pharmacol. 2016
Semax, an analogue of adrenocorticotropin (4-10), binds specifically and increases levels of brain-derived neurotrophic factor protein in rat basal forebrain J Neurochem. 2006
The occurrence of putative cognitive enhancing research peptides in seized pharmaceutical preparations: An incentive for controlling agencies to prepare for future encounters of the kind Drug Test Anal. 2020
Natural and hybrid ("chimeric") stable regulatory glyproline peptides Pathophysiology. 2005
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions J Am Acad Orthop Surg Glob Res Rev. 2026
Bulk Drug Substances Nominated for Use in Compounding Under Section 503A of the Federal Food, Drug, and Cosmetic Act (updated May 14, 2026) FDA. 2026
PubMed search: Selank AND Semax (14 records, none an experiment on the combination; searched 22 October 2026) PubMed. 2026
World Anti-Doping Code International Standard: Prohibited List 2026 WADA. 2026

Last reviewed October 22, 2026 by the Amiravo editorial team. Editorial policy · Report an error